Coordination polymer coated mesoporous silica nanoparticles for pH-responsive drug release

Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 24(2012), 48 vom: 18. Dez., Seite 6433-7
1. Verfasser: Xing, Lei (VerfasserIn)
Weitere Verfasser: Zheng, Haoquan, Cao, Yuanyuan, Che, Shunai
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Polymers Silicon Dioxide 7631-86-9 Topotecan 7M7YKX2N15
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520 |a Coordination polymer coated mesoporous silica nanoparticles for drug delivery are successfully synthesized. The system ensures that drugs are stored in the mesopores under a physiological environment. Upon H(+) stimulus in the endosomal and lysosomal compartments, the drugs are released into the intracellular organelles of cancer cells, effectively killing the cells 
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