Cosuspensions of microcrystals and engineered microparticles for uniform and efficient delivery of respiratory therapeutics from pressurized metered dose inhalers

Engineered porous phospholipid microparticles with aerodynamic diameters in the respirable range of 1-2 μm were cosuspended in 1,1,1,2-tetrafluoroethane, a propellant, with microcrystals of glycopyrrolate, formoterol fumarate dihydrate, or Mometasone furoate-three drugs with different solubilities i...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 28(2012), 42 vom: 23. Okt., Seite 15015-23
1. Verfasser: Vehring, Reinhard (VerfasserIn)
Weitere Verfasser: Lechuga-Ballesteros, David, Joshi, Vidya, Noga, Brian, Dwivedi, Sarvajna K
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Ethanolamines Fumarates Hydrocarbons, Fluorinated Phospholipids Pregnadienediols Mometasone Furoate 04201GDN4R Water 059QF0KO0R mehr... norflurane DH9E53K1Y8 Glycopyrrolate V92SO9WP2I Formoterol Fumarate W34SHF8J2K