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231224s2012 xx |||||o 00| ||eng c |
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Barthes, Julien
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Stretch-induced biodegradation of polyelectrolyte multilayer films for drug release
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| 264 |
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1 |
|c 2012
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
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|2 rdacarrier
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| 500 |
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|a Date Completed 14.02.2013
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|a Date Revised 19.11.2015
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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| 520 |
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|a The design of stimuli-responsive polymer assemblies for the controlled release of bioactive molecules has raised considerable interest these two last decades. Herein, we report the design of mechanically responsive drug-releasing films made of polyelectrolyte multilayers. A layer-by-layer (LbL) reservoir containing biodegradable polyelectrolytes is capped with a mechanosensitive LbL barrier and responds to stretching by a total enzymatic degradation of the film. This strategy is successfully applied for the release in solution of an anticancer drug initially loaded within the architecture
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| 650 |
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4 |
|a Journal Article
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| 650 |
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4 |
|a Research Support, Non-U.S. Gov't
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| 650 |
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|a Antineoplastic Agents, Phytogenic
|2 NLM
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| 650 |
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7 |
|a Electrolytes
|2 NLM
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| 650 |
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7 |
|a Membranes, Artificial
|2 NLM
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| 650 |
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7 |
|a Polymers
|2 NLM
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| 650 |
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7 |
|a Paclitaxel
|2 NLM
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| 650 |
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7 |
|a P88XT4IS4D
|2 NLM
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| 700 |
1 |
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|a Mertz, Damien
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Bach, Charlotte
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Metz-Boutigue, Marie-Hélène
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Senger, Bernard
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Voegel, Jean-Claude
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Schaaf, Pierre
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Lavalle, Philippe
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 28(2012), 38 vom: 25. Sept., Seite 13550-4
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
1 |
8 |
|g volume:28
|g year:2012
|g number:38
|g day:25
|g month:09
|g pages:13550-4
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