Microcosmic mechanisms for protein incomplete release and stability of various amphiphilic mPEG-PLA microspheres

The microcosmic mechanisms of protein (recombinant human growth hormone, rhGH) incomplete release and stability from amphiphilic poly(monomethoxypolyethylene glycol-co-D,L-lactide) (mPEG-PLA, PELA) microspheres were investigated. PELA with different hydrophilicities (PELA-1, PELA-2, and PELA-3) base...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 28(2012), 39 vom: 02. Okt., Seite 13984-92
1. Verfasser: Wei, Yi (VerfasserIn)
Weitere Verfasser: Wang, Yu Xia, Wang, Wei, Ho, Sa V, Qi, Feng, Ma, Guang Hui, Su, Zhi Guo
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Polyesters Polymers Recombinant Proteins Surface-Active Agents Human Growth Hormone 12629-01-5 Lactic Acid 33X04XA5AT mehr... Polyethylene Glycols 3WJQ0SDW1A poly(lactide) 459TN2L5F5 monomethoxypolyethylene glycol 9004-74-4