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231224s2012 xx ||||| 00| ||chi c |
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|a pubmed25n0735.xml
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|a (DE-627)NLM22059497X
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|a (NLM)22932009
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a chi
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| 100 |
1 |
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|a Zhuang, Xue-ling
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Maternal-neonatal vitamin D status and related factors
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| 264 |
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1 |
|c 2012
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 04.04.2013
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|a Date Revised 13.08.2018
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a OBJECTIVE: To determine the relationship between maternal and neonatal vitamin D status and related factors
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|a METHOD: Serum 25-(OH)D levels were measured by ELISA in 499 pregnant women at 30 - 37 weeks gestation and in cord blood of their infants born at term (37 - 42 wk gestation) in Southeastern China at 28.9°N latitude. One-way analysis of variance (ANOVA) was used to explore maternal and neonatal vitamin D levels by season. Pearson linear and linear regression of partial correlation was used to analyze the relationship between maternal and neonatal 25-(OH) D levels. The multiple factors related to maternal vitamin D status was assessed by binary logistic regression
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| 520 |
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|a RESULT: The levels of serum 25-(OH)D were (33.0 ± 13.4) nmol/L in mothers and (31.0 ± 12.5) nmol/L in their newborns. Serum 25-(OH)D < 50 nmol/L was shown in 88.8% of mothers and 91.2% of their neonates. Both maternal and neonatal 25-(OH)D levels varied with season (Ps = 0.000). Vitamin D level was the lowest in spring, with the 25-(OH)D concentration < 50 nmol/L in 98.6% of mothers and 99.3% of their neonates. The highest vitamin D level was presented in fall, but there were still 64.0% of mothers and 75.0% of neonates with 25-(OH)D < 50 nmol/L. Except for season, calcium-vitamin D supplement and intake of egg ≥ 600 g per week during pregnancy benefited to improve maternal vitamin D level [25-(OH)D ≥ 50 nmol/L] [OR = 2.3 (95%CI:1.0, 5.3), 3.4 (95%CI:1.2, 9.9) respectively]. There was a positive correlation between maternal and neonatal 25-(OH)D measures in the sample as a whole (r = 0.45, P = 0.000, N = 499), the correlation was of no statistical significance when maternal serum 25-(OH)D was ≤ 25 nmol/L
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|a CONCLUSION: Hypovitaminosis D was common in late pregnant mothers and their newborns in southeastern China, especially in spring. Vitamin D supplement and intake of vitamin D-rich food were beneficial to improvement of maternal vitamin D level. There was a moderate and positive correlation between maternal and neonatal 25-(OH)D concentrations in this population. The correlation was lost when maternal serum 25-(OH)D ≤ 25 nmol/L
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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7 |
|a Vitamin D
|2 NLM
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| 650 |
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7 |
|a 1406-16-2
|2 NLM
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| 650 |
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7 |
|a 25-hydroxyvitamin D
|2 NLM
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| 650 |
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7 |
|a A288AR3C9H
|2 NLM
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| 650 |
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7 |
|a Calcium
|2 NLM
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| 650 |
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|a SY7Q814VUP
|2 NLM
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| 700 |
1 |
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|a Zhu, Zhi-wei
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhu, Dong-bo
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Chen, Li-qin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhao, Zheng-yan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Shao, Jie
|e verfasserin
|4 aut
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| 773 |
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8 |
|i Enthalten in
|t Zhonghua er ke za zhi = Chinese journal of pediatrics
|d 1960
|g 50(2012), 7 vom: 29. Juli, Seite 498-503
|w (DE-627)NLM136249191
|x 0578-1310
|7 nnns
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| 773 |
1 |
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|g volume:50
|g year:2012
|g number:7
|g day:29
|g month:07
|g pages:498-503
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|a AR
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|d 50
|j 2012
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|h 498-503
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