Hippocampal CA1 pyramidal neurons of Mecp2 mutant mice show a dendritic spine phenotype only in the presymptomatic stage

Alterations in dendritic spines have been documented in numerous neurodevelopmental disorders, including Rett Syndrome (RTT). RTT, an X chromosome-linked disorder associated with mutations in MECP2, is the leading cause of intellectual disabilities in women. Neurons in Mecp2-deficient mice show lowe...

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Veröffentlicht in:Neural plasticity. - 1998. - 2012(2012) vom: 01., Seite 976164
1. Verfasser: Chapleau, Christopher A (VerfasserIn)
Weitere Verfasser: Boggio, Elena Maria, Calfa, Gaston, Percy, Alan K, Giustetto, Maurizio, Pozzo-Miller, Lucas
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Carbocyanines Coloring Agents Mecp2 protein, mouse Methyl-CpG-Binding Protein 2 3,3'-dioctadecylindocarbocyanine 40957-95-7