Versatile gradients of covalently bound proteins on microstructured substrates

Versatile gradients of covalently bound proteins on microstructured substrates

In this work, we propose an easy method to produce highly tunable gradients of covalently bound proteins on topographically modified poly(methyl methacrylate). We used a microfluidic approach to obtain linear gradients with high slope (0.5 pmol·cm(-2)·mm(-1)), relevant at the single-cell level. Thes...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 28(2012), 38 vom: 25. Sept., Seite 13688-97
1. Verfasser: Comelles, Jordi (VerfasserIn)
Weitere Verfasser: Hortigüela, Verónica, Samitier, Josep, Martínez, Elena
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Proteins Polymethyl Methacrylate 9011-14-7