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231224s2012 xx |||||o 00| ||eng c |
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|a 10.1007/s10646-012-0989-x
|2 doi
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|a pubmed25n0734.xml
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|a (NLM)22903291
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|a DE-627
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|c DE-627
|e rakwb
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|a eng
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|a Holladay, Jeremy P
|e verfasserin
|4 aut
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|a Dosing of adult pigeons with as little as one #9 lead pellet caused severe δ-ALAD depression, suggesting potential adverse effects in wild populations
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|c 2012
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 17.03.2013
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|a Date Revised 21.10.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Avian wildlife species commonly ingest lead (Pb) spent shot or bullet fragments as grit or mistakenly as food. In previous studies in our laboratory and others, the toxicity varied based on the diet as well as type and quantity of Pb ingested. In the current study, domestic pigeons were gavaged with 1, 2, or 3 Pb pellets and then followed with weekly radiographs and blood physiologic endpoints for 28 days. Pellet retention decreased by roughly 50 % per week as pellets were either absorbed or excreted, except for week 4 where pellet number no longer was diminished. Size of retained pellets visually decreased over retention time. Birds dosed with a single #9 pellet showed mean blood Pb levels over 80 times higher than those of the controls, verifying Pb pellet absorption from the gut. A single Pb pellet also reduced plasma δ-aminolevulinic acid dehydratase (δ-ALAD) activity by over 80 % compared to controls, suggesting the potential for population injury in Pb pellet-exposed pigeons
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|a Journal Article
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|a Research Support, U.S. Gov't, Non-P.H.S.
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|a Environmental Pollutants
|2 NLM
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|a Lead
|2 NLM
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|a 2P299V784P
|2 NLM
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|a Porphobilinogen Synthase
|2 NLM
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|a EC 4.2.1.24
|2 NLM
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|a Nisanian, Mandy
|e verfasserin
|4 aut
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|a Williams, Susan
|e verfasserin
|4 aut
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|a Tuckfield, R Cary
|e verfasserin
|4 aut
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|a Kerr, Richard
|e verfasserin
|4 aut
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|a Jarrett, Timothy
|e verfasserin
|4 aut
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|a Tannenbaum, Lawrence
|e verfasserin
|4 aut
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| 700 |
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|a Holladay, Steven D
|e verfasserin
|4 aut
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| 700 |
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|a Sharma, Ajay
|e verfasserin
|4 aut
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| 700 |
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|a Gogal, Robert M
|c Jr
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Ecotoxicology (London, England)
|d 1998
|g 21(2012), 8 vom: 01. Nov., Seite 2331-7
|w (DE-627)NLM098212214
|x 1573-3017
|7 nnns
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| 773 |
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|g volume:21
|g year:2012
|g number:8
|g day:01
|g month:11
|g pages:2331-7
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|u http://dx.doi.org/10.1007/s10646-012-0989-x
|3 Volltext
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