Continuous thermal collapse of the intrinsically disordered protein tau is driven by its entropic flexible domain

The tau protein belongs to the category of Intrinsically Disordered Proteins (IDP), which in their native state lack a folded structure and fluctuate between many conformations. In its physiological state, tau helps nucleating and stabilizing the microtubules' (MTs) surfaces in the axons of the...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 28(2012), 37 vom: 18. Sept., Seite 13405-10
1. Verfasser: Ciasca, Gabriele (VerfasserIn)
Weitere Verfasser: Campi, Gaetano, Battisti, Anna, Rea, Giuseppina, Rodio, Marina, Papi, Massimiliano, Pernot, Petra, Tenenbaum, Alexander, Bianconi, Antonio
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't tau Proteins