Metal ion controlled self-assembly of a chemically reengineered protein drug studied by small-angle X-ray scattering

Precise control of the oligomeric state of proteins is of central importance for biological function and for the properties of biopharmaceutical drugs. Here, the self-assembly of 2,2'-bipyridine conjugated monomeric insulin analogues, induced through coordination to divalent metal ions, was stu...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 28(2012), 33 vom: 21. Aug., Seite 12159-70
1. Verfasser: Nygaard, Jesper (VerfasserIn)
Weitere Verfasser: Munch, Henrik K, Thulstrup, Peter W, Christensen, Niels J, Hoeg-Jensen, Thomas, Jensen, Knud J, Arleth, Lise
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Insulin 2,2'-Dipyridyl 551W113ZEP Iron E1UOL152H7 Zinc J41CSQ7QDS