Metal ion controlled self-assembly of a chemically reengineered protein drug studied by small-angle X-ray scattering
Precise control of the oligomeric state of proteins is of central importance for biological function and for the properties of biopharmaceutical drugs. Here, the self-assembly of 2,2'-bipyridine conjugated monomeric insulin analogues, induced through coordination to divalent metal ions, was stu...
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Bibliographische Detailangaben
Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 28(2012), 33 vom: 21. Aug., Seite 12159-70
|
1. Verfasser: |
Nygaard, Jesper
(VerfasserIn) |
Weitere Verfasser: |
Munch, Henrik K,
Thulstrup, Peter W,
Christensen, Niels J,
Hoeg-Jensen, Thomas,
Jensen, Knud J,
Arleth, Lise |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2012
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Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
|
Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Insulin
2,2'-Dipyridyl
551W113ZEP
Iron
E1UOL152H7
Zinc
J41CSQ7QDS |