Superhydrophilic zwitterionic polymers stabilize liposomes

Nonionic polyethylene glycol (PEG) as a stealth polymer destabilizes liposomes due to its amphiphilic property. As a result, PEGylated liposomes have to be further stabilized, such as by using a large amount cholesterol. This is a long existing dilemma faced by PEG. In this work, we show that zwitte...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 28(2012), 31 vom: 07. Aug., Seite 11625-32
1. Verfasser: Cao, Zhiqiang (VerfasserIn)
Weitere Verfasser: Zhang, Lei, Jiang, Shaoyi
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Antineoplastic Agents Delayed-Action Preparations Fluoresceins Fluorescent Dyes Liposomes 6-carboxyfluorescein 3301-79-9 mehr... Betaine 3SCV180C9W Polyethylene Glycols 3WJQ0SDW1A Doxorubicin 80168379AG Cholesterol 97C5T2UQ7J