Enhancement of Hsp70 synthesis protects common carp, Cyprinus carpio L., against lethal ammonia toxicity

© 2012 Blackwell Publishing Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Journal of fish diseases. - 1998. - 35(2012), 8 vom: 26. Aug., Seite 563-8
1. Verfasser: Sung, Y Y (VerfasserIn)
Weitere Verfasser: Roberts, R J, Bossier, P
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Journal of fish diseases
Schlagworte:Journal Article Research Support, Non-U.S. Gov't HSP70 Heat-Shock Proteins Plant Extracts Water Pollutants, Chemical Ammonia 7664-41-7
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520 |a Exposure to TEX-OE®, a patented extract of the prickly pear cactus (Opuntia ficus indica) containing chaperone-stimulating factor, was shown to protect common carp, Cyprinus carpio L., fingerlings against acute ammonia stress. Survival was enhanced twofold from 50% to 95% after exposure to 5.92 mg L(-1) NH(3) , a level determined in the ammonia challenge bioassay as the 1-h LD50 concentration for this species. Survival of TEX-OE®-pre-exposed fish was enhanced by 20% over non-exposed controls during lethal ammonia challenge (14.21 mg L(-1)  NH(3) ). Increase in the levels of gill and muscle Hsp70 was evident in TEX-OE®-pre-exposed fish but not in the unexposed controls, indicating that application of TEX-OE® accelerated carp endogenous Hsp70 synthesis during ammonia perturbation. Protection against ammonia was correlated with Hsp70 accretion 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a HSP70 Heat-Shock Proteins  |2 NLM 
650 7 |a Plant Extracts  |2 NLM 
650 7 |a Water Pollutants, Chemical  |2 NLM 
650 7 |a Ammonia  |2 NLM 
650 7 |a 7664-41-7  |2 NLM 
700 1 |a Roberts, R J  |e verfasserin  |4 aut 
700 1 |a Bossier, P  |e verfasserin  |4 aut 
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