|
|
|
|
LEADER |
01000naa a22002652 4500 |
001 |
NLM218773234 |
003 |
DE-627 |
005 |
20231224041310.0 |
007 |
cr uuu---uuuuu |
008 |
231224s2012 xx |||||o 00| ||eng c |
024 |
7 |
|
|a 10.1002/mrc.3835
|2 doi
|
028 |
5 |
2 |
|a pubmed24n0729.xml
|
035 |
|
|
|a (DE-627)NLM218773234
|
035 |
|
|
|a (NLM)22715068
|
040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
041 |
|
|
|a eng
|
100 |
1 |
|
|a Feng, Wenqing
|e verfasserin
|4 aut
|
245 |
1 |
0 |
|a Characterization of an unusual ring-contraction degradant of the antifungal agent posaconazole
|
264 |
|
1 |
|c 2012
|
336 |
|
|
|a Text
|b txt
|2 rdacontent
|
337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
500 |
|
|
|a Date Completed 01.04.2013
|
500 |
|
|
|a Date Revised 25.11.2013
|
500 |
|
|
|a published: Print-Electronic
|
500 |
|
|
|a Citation Status MEDLINE
|
520 |
|
|
|a Copyright © 2012 John Wiley & Sons, Ltd.
|
520 |
|
|
|a Posaconazole, a clinically useful antifungal agent, has several known oxidative degradation products involving the piperazine ring near the center of the molecule. A novel degradant was recently isolated and characterized spectroscopically as a novel ring-contraction product incorporating a dihydroimidazolium moiety in lieu of the normally present piperazine ring
|
650 |
|
4 |
|a Letter
|
650 |
|
7 |
|a Antifungal Agents
|2 NLM
|
650 |
|
7 |
|a Triazoles
|2 NLM
|
650 |
|
7 |
|a posaconazole
|2 NLM
|
650 |
|
7 |
|a 6TK1G07BHZ
|2 NLM
|
700 |
1 |
|
|a Hilton, Bruce D
|e verfasserin
|4 aut
|
700 |
1 |
|
|a Zhong, Wendy
|e verfasserin
|4 aut
|
700 |
1 |
|
|a Yang, Jiong
|e verfasserin
|4 aut
|
700 |
1 |
|
|a Yang, Xi
|e verfasserin
|4 aut
|
700 |
1 |
|
|a Tong, Weidong
|e verfasserin
|4 aut
|
700 |
1 |
|
|a Martin, Gary E
|e verfasserin
|4 aut
|
773 |
0 |
8 |
|i Enthalten in
|t Magnetic resonance in chemistry : MRC
|d 1985
|g 50(2012), 8 vom: 16. Aug., Seite 576-9
|w (DE-627)NLM098179667
|x 1097-458X
|7 nnns
|
773 |
1 |
8 |
|g volume:50
|g year:2012
|g number:8
|g day:16
|g month:08
|g pages:576-9
|
856 |
4 |
0 |
|u http://dx.doi.org/10.1002/mrc.3835
|3 Volltext
|
912 |
|
|
|a GBV_USEFLAG_A
|
912 |
|
|
|a SYSFLAG_A
|
912 |
|
|
|a GBV_NLM
|
912 |
|
|
|a GBV_ILN_350
|
951 |
|
|
|a AR
|
952 |
|
|
|d 50
|j 2012
|e 8
|b 16
|c 08
|h 576-9
|