Characterization of an unusual ring-contraction degradant of the antifungal agent posaconazole

Copyright © 2012 John Wiley & Sons, Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Magnetic resonance in chemistry : MRC. - 1985. - 50(2012), 8 vom: 16. Aug., Seite 576-9
1. Verfasser: Feng, Wenqing (VerfasserIn)
Weitere Verfasser: Hilton, Bruce D, Zhong, Wendy, Yang, Jiong, Yang, Xi, Tong, Weidong, Martin, Gary E
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Magnetic resonance in chemistry : MRC
Schlagworte:Letter Antifungal Agents Triazoles posaconazole 6TK1G07BHZ
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520 |a Posaconazole, a clinically useful antifungal agent, has several known oxidative degradation products involving the piperazine ring near the center of the molecule. A novel degradant was recently isolated and characterized spectroscopically as a novel ring-contraction product incorporating a dihydroimidazolium moiety in lieu of the normally present piperazine ring 
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700 1 |a Yang, Xi  |e verfasserin  |4 aut 
700 1 |a Tong, Weidong  |e verfasserin  |4 aut 
700 1 |a Martin, Gary E  |e verfasserin  |4 aut 
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