|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM218739532 |
| 003 |
DE-627 |
| 005 |
20231224041217.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231224s2012 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1002/adma.201104891
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n0729.xml
|
| 035 |
|
|
|a (DE-627)NLM218739532
|
| 035 |
|
|
|a (NLM)22711427
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Railsback, Justin G
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Weakly charged cationic nanoparticles induce DNA bending and strand separation
|
| 264 |
|
1 |
|c 2012
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 10.12.2012
|
| 500 |
|
|
|a Date Revised 30.09.2020
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
|
| 520 |
|
|
|a Weakly charged cationic nanoparticles cause structural changes including local denaturing and compaction to DNA under mild conditions. The charged ligands bind to the phosphate backbone of DNA and the uncharged ligands penetrate the helix and disrupt base pairing. Mobility shifts in electrophoresis, molecular dynamics, and UV-vis spectrophotometry give clues to the details of the interactions
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, U.S. Gov't, Non-P.H.S.
|
| 650 |
|
7 |
|a Cations
|2 NLM
|
| 650 |
|
7 |
|a Gold
|2 NLM
|
| 650 |
|
7 |
|a 7440-57-5
|2 NLM
|
| 650 |
|
7 |
|a DNA
|2 NLM
|
| 650 |
|
7 |
|a 9007-49-2
|2 NLM
|
| 700 |
1 |
|
|a Singh, Abhishek
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Pearce, Ryan C
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a McKnight, Timothy E
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Collazo, Ramón
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Sitar, Zlatko
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Yingling, Yaroslava G
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Melechko, Anatoli V
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 24(2012), 31 vom: 16. Aug., Seite 4261-5
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
|
| 773 |
1 |
8 |
|g volume:24
|g year:2012
|g number:31
|g day:16
|g month:08
|g pages:4261-5
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1002/adma.201104891
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 24
|j 2012
|e 31
|b 16
|c 08
|h 4261-5
|