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231224s2012 xx |||||o 00| ||eng c |
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|a 10.1016/j.plantsci.2012.04.008
|2 doi
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|a pubmed25n0728.xml
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|a (NLM)22682562
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|a DE-627
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|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Horiguchi, Gorou
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Ribosomes and translation in plant developmental control
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|c 2012
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 11.01.2013
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|a Date Revised 09.04.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
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|a Ribosomes play a basic housekeeping role in global translation. However, a number of ribosomal-protein-defective mutants show common and rare developmental phenotypes including growth defects, changes in leaf development, and auxin-related phenotypes. This suggests that translational regulation may be occurring during development. In addition, proteomic and bioinformatic analyses have demonstrated a high heterogeneity in ribosome composition. Although this might be a sign of unequal roles of individual ribosomal proteins, it does not explain every ribosomal-protein-defective phenotype. Moreover, comprehensive interpretations concerning the relationship between ribosomal-protein-defective phenotypes and molecular changes in ribosome status are lacking. In this review, we address these phenotypes based on three models, ribosome insufficiency, heterogeneity, and aberrancy, to consider how ribosomes play developmental roles. We propose that the three models are not mutually exclusive, and ribosomal-protein-defective phenotypes can be explained with one or more of these models. The three models with reference to genetic, biochemical, and bioinformatic knowledge will serve as a foundation for future studies of translational regulation
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Review
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| 650 |
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|a Ribosomal Proteins
|2 NLM
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| 700 |
1 |
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|a Van Lijsebettens, Mieke
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Candela, Héctor
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Micol, José Luis
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tsukaya, Hirokazu
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Plant science : an international journal of experimental plant biology
|d 1985
|g 191-192(2012) vom: 15. Aug., Seite 24-34
|w (DE-627)NLM098174193
|x 1873-2259
|7 nnas
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| 773 |
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|g volume:191-192
|g year:2012
|g day:15
|g month:08
|g pages:24-34
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|u http://dx.doi.org/10.1016/j.plantsci.2012.04.008
|3 Volltext
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