Divergent roles of p75NTR and Trk receptors in BDNF's effects on dendritic spine density and morphology
Activation of TrkB receptors by brain-derived neurotrophic factor (BDNF) followed by MAPK/ERK signaling increases dendritic spine density and the proportion of mature spines in hippocampal CA1 pyramidal neurons. Considering the opposing actions of p75(NTR) and Trk receptors in several BDNF actions o...
| Veröffentlicht in: | Neural plasticity. - 1998. - 2012(2012) vom: 01., Seite 578057 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
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2012
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| Zugriff auf das übergeordnete Werk: | Neural plasticity |
| Schlagworte: | Journal Article Research Support, N.I.H., Extramural Brain-Derived Neurotrophic Factor Nerve Growth Factors Nerve Tissue Proteins Receptors, Growth Factor Receptors, Nerve Growth Factor Ngfr protein, rat 136958-07-1 Receptor, trkB |
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