Morphology effects on the biofunctionalization of nanostructured ZnO

A stepwise surface functionalization methodology was applied to nanostructured ZnO films grown by metal organic chemical vapor deposition (MOCVD) having three different surface morphologies (i.e., nanorod layers (ZnO films-N), rough surface films (ZnO films-R), and planar surface films (ZnO films-P)...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 28(2012), 21 vom: 29. Mai, Seite 7947-51
1. Verfasser: Cao, Yan (VerfasserIn)
Weitere Verfasser: Galoppini, Elena, Reyes, Pavel Ivanoff, Duan, Ziqing, Lu, Yicheng
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't DNA, Single-Stranded Membranes, Artificial Sulfhydryl Compounds Palmitic Acid 2V16EO95H1 Zinc Oxide SOI2LOH54Z
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520 |a A stepwise surface functionalization methodology was applied to nanostructured ZnO films grown by metal organic chemical vapor deposition (MOCVD) having three different surface morphologies (i.e., nanorod layers (ZnO films-N), rough surface films (ZnO films-R), and planar surface films (ZnO films-P). The films were grown on glass substrates and on the sensing area of a quartz crystal microbalance (nano-QCM). 16-(2-Pyridyldithiol)-hexadecanoic acid (PDHA) was bound to ZnO films-N, -R, and -P through the carboxylic acid unit, followed by a nucleophilic displacement of the 2-pyridyldithiol moiety by single-stranded DNA capped with a thiol group (SH-ssDNA). The resulting ssDNA-functionalized films were hybridized with complementary ssDNA tagged with fluorescein (ssDNA-Fl). In a selectivity control experiment, no hybridization occurred upon treatment with non complementary DNA. The ZnO films' surface functionalization, characterized by FT-IR-ATR and fluorescence spectroscopy and detected on the nano-QCM, was successful on films-N and -R but was barely detectable on the planar surface of films-P 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
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650 7 |a Palmitic Acid  |2 NLM 
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650 7 |a Zinc Oxide  |2 NLM 
650 7 |a SOI2LOH54Z  |2 NLM 
700 1 |a Galoppini, Elena  |e verfasserin  |4 aut 
700 1 |a Reyes, Pavel Ivanoff  |e verfasserin  |4 aut 
700 1 |a Duan, Ziqing  |e verfasserin  |4 aut 
700 1 |a Lu, Yicheng  |e verfasserin  |4 aut 
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