Absolute configurations of C34 and C35 of antibiotic niphimycin A

Copyright © 2012 John Wiley & Sons, Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Magnetic resonance in chemistry : MRC. - 1985. - 50(2012), 5 vom: 07. Mai, Seite 347-9
1. Verfasser: Laskowski, Tomasz (VerfasserIn)
Weitere Verfasser: Rafiński, Zbigniew, Sowiński, Paweł, Pawlak, Jan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Magnetic resonance in chemistry : MRC
Schlagworte:Journal Article Anti-Bacterial Agents Guanidines niphimycin 12676-71-0
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520 |a The relative configurations of four stereogenic centers of the C33-C42 fragment of niphimycin A were assigned as 2S*, 3R*, 4S* and 6S*, based upon (1)H NMR analysis with double-quantum filtered COSY and nuclear Overhauser spectroscopy experiments. These data were then correlated with absolute configurations at C36 and C38 of niphimycin A, which were declared previously as 36S and 38S [3]. This allowed for the assignment of the absolute configurations at C34 and C35 of niphimycin A as 34S and 35R 
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