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231224s2012 xx |||||o 00| ||eng c |
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|a 10.1111/j.1939-165X.2011.00388.x
|2 doi
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|a pubmed25n0715.xml
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|a (NLM)22250805
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Caniatti, Mario
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Diagnostic accuracy of brush cytology in canine chronic intranasal disease
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|c 2012
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 02.08.2012
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|a Date Revised 20.10.2016
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2012 American Society for Veterinary Clinical Pathology.
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|a BACKGROUND: Most cases of canine chronic intranasal disease cannot be differentiated based on clinical examination alone, and biopsy is often required for a definitive diagnosis. Nonsurgical cytologic and histologic biopsy techniques represent desirable diagnostic approaches
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|a OBJECTIVE: The aim of this retrospective study was to determine the diagnostic accuracy of brush cytology in differentiating non-neoplastic and neoplastic diseases in dogs with chronic intranasal disease
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| 520 |
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|a METHODS: Cytologic samples of lesions in dogs with chronic intranasal disease were obtained by brushing over a 12-year period. All dogs had complete physical examinations as well as radiographic, rhinoscopic, and cytologic evaluation. Histologic diagnosis, follow-up clinical information, or both were used as the gold standard, and dogs free of disease or with no progression of disease at 1 year were considered negative for neoplasia. Indicators of performance of brush cytology in detecting neoplasia were calculated and included sensitivity, specificity, positive and negative likelihood ratios, and diagnostic odds ratio
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|a RESULTS: Samples of nasal brushings from 138 dogs were evaluated. Of 62 cases of neoplastic disease, true-positive and false-negative diagnoses were made using cytologic evaluation in 44 (71.0%) and 18 (29.0%) cases, respectively. False-negative diagnoses of neoplasia were not attributed to low cellularity, but to the presence of inflammatory cells that masked neoplastic cells. Brush cytology had a sensitivity of 0.71, specificity of 0.99, positive likelihood ratio of 53.94, negative likelihood ratio of 0.29, and diagnostic odds ratio of 188.33
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|a CONCLUSIONS: Brush cytology has good diagnostic accuracy for chronic intranasal lesions in dogs
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|a Journal Article
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|a da Cunha, Nazaré Pinto
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Avallone, Giancarlo
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Romussi, Stefano
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Mortellaro, Carlo Maria
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tranquillo, Vito
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ghisleni, Gabriele
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Veterinary clinical pathology
|d 1975
|g 41(2012), 1 vom: 08. März, Seite 133-40
|w (DE-627)NLM098159984
|x 1939-165X
|7 nnns
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| 773 |
1 |
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|g volume:41
|g year:2012
|g number:1
|g day:08
|g month:03
|g pages:133-40
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