Charge transfer through modified peptide nucleic acids

Charge transfer through modified peptide nucleic acids

© 2012 American Chemical Society

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 28(2012), 4 vom: 31. Jan., Seite 1971-81
1. Verfasser: Wierzbinski, Emil (VerfasserIn)
Weitere Verfasser: de Leon, Arnie, Davis, Kathryn L, Bezer, Silvia, Wolak, Matthäus A, Kofke, Matthew J, Schlaf, Rudy, Achim, Catalina, Waldeck, David H
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, U.S. Gov't, Non-P.H.S. Peptide Nucleic Acids 2,2'-Dipyridyl 551W113ZEP Zinc J41CSQ7QDS
Beschreibung
Zusammenfassung:© 2012 American Chemical Society
We studied the charge transfer properties of bipyridine-modified peptide nucleic acid (PNA) in the absence and presence of Zn(II). Characterization of the PNA in solution showed that Zn(II) interacts with the bipyridine ligands, but the stability of the duplexes was not affected significantly by the binding of Zn(II). The charge transfer properties of these molecules were examined by electrochemistry for self-assembled monolayers of ferrocene-terminated PNAs and by conductive probe atomic force microscopy for cysteine-terminated PNAs. Both electrochemical and single molecular studies showed that the bipyridine modification and Zn(II) binding do not affect significantly the charge transfer of the PNA duplexes
Beschreibung:Date Completed 23.05.2012
Date Revised 21.11.2013
published: Print-Electronic
ErratumIn: Langmuir. 2012 Oct 2;28(39):14107
Citation Status MEDLINE
ISSN:1520-5827
DOI:10.1021/la204445u