|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM214007286 |
| 003 |
DE-627 |
| 005 |
20231224022725.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231224s2012 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1021/la2037668
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n0713.xml
|
| 035 |
|
|
|a (DE-627)NLM214007286
|
| 035 |
|
|
|a (NLM)22185602
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Fujii, Shota
|e verfasserin
|4 aut
|
| 245 |
1 |
2 |
|a A stimulus-responsive shape-persistent micelle bearing a calix[4]arene building block
|b reversible pH-dependent transition between spherical and cylindrical forms
|
| 264 |
|
1 |
|c 2012
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 08.06.2012
|
| 500 |
|
|
|a Date Revised 14.02.2012
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status PubMed-not-MEDLINE
|
| 520 |
|
|
|a A series of cationic calix[4]arene-based lipids with alkyl chains of varying length were newly synthesized, and the ones with propyl and hexyl tails, denoted by CaL[4]C3 and C6, respectively, were found to form spherical micelles at low pH (protonated state of the amine headgroup). Upon deprotonation with increasing pH, CaL[4]C3 showed a sphere-to-cylinder transition, while CaL[4]C6 changed from sphere, to cylinder, to monolayer vesicle. Synchrotron small-angle X-ray scattering (SAXS) patterns from both spherical and cylindrical CaL[4]C3 micelles exhibited a sharp intensity minimum, indicating shape monodispersity. The monodispersity of the CaL[4]C3 spherical micelles was further confirmed by analytical ultracentrifugation (AUC). SAXS, AUC, and static light scattering agreeingly indicated an aggregation number of 6. In contrast, CaL[4]C6 exhibited polydispersity with an average aggregation number of 12. When the number of carbons of the alkyl chain was increased to 9 (CaL[4]C9), cylinder formed at low pH, while at high pH, no clear morphology could be observed. The present results indicate that a very precise combination of tail length, head volume, and rigidity of the building block is required to produce shape-persistent micelles and that the shape-persistence can be maintained upon a structural transition. An attempt to reconstruct a molecular model for the spherical CaL[4]C3 micelle was made with an ab initio shape determining program
|
| 650 |
|
4 |
|a Journal Article
|
| 700 |
1 |
|
|a Sanada, Yusuke
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Nishimura, Tomoki
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Akiba, Isamu
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Sakurai, Kazuo
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Yagi, Naoto
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Mylonas, Efstratios
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1999
|g 28(2012), 6 vom: 14. Feb., Seite 3092-101
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
|
| 773 |
1 |
8 |
|g volume:28
|g year:2012
|g number:6
|g day:14
|g month:02
|g pages:3092-101
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1021/la2037668
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_22
|
| 912 |
|
|
|a GBV_ILN_350
|
| 912 |
|
|
|a GBV_ILN_721
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 28
|j 2012
|e 6
|b 14
|c 02
|h 3092-101
|