Redox-responsive molecular nanoreservoirs for controlled intracellular anticancer drug delivery based on magnetic nanoparticles

Redox-responsive molecular nanoreservoirs for controlled intracellular anticancer drug delivery based on magnetic nanoparticles

Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 24(2012), 3 vom: 17. Jan., Seite 431-5
1. Verfasser: Luo, Zhong (VerfasserIn)
Weitere Verfasser: Cai, Kaiyong, Hu, Yan, Li, Jinghua, Ding, Xingwei, Zhang, Beilu, Xu, Dawei, Yang, Weihu, Liu, Peng
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't endocytosis endosomal escape intracellular drug delivery magnetic nanoparticles redox response Antineoplastic Agents Drug Carriers Magnetite Nanoparticles mehr... beta-Cyclodextrins Doxorubicin 80168379AG Polyethyleneimine 9002-98-6 betadex JV039JZZ3A
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245 1 0 |a Redox-responsive molecular nanoreservoirs for controlled intracellular anticancer drug delivery based on magnetic nanoparticles 
264 1 |c 2012 
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500 |a Date Completed 18.08.2015 
500 |a Date Revised 30.09.2020 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. 
520 |a A novel redox responsive controlled drug release system based on magnetic nanoparticles for efficient intracellular anticancer drug delivery is fabricated. Disulfide bonds are employed as intermediate linkers to immobilize PEI/β-CD molecules as nanoreservoirs for drug loading onto magnetic nanoparticles. The endocytotic pathway and endosomal escape of the smart controlled drug release system is proposed 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a endocytosis 
650 4 |a endosomal escape 
650 4 |a intracellular drug delivery 
650 4 |a magnetic nanoparticles 
650 4 |a redox response 
650 7 |a Antineoplastic Agents  |2 NLM 
650 7 |a Drug Carriers  |2 NLM 
650 7 |a Magnetite Nanoparticles  |2 NLM 
650 7 |a beta-Cyclodextrins  |2 NLM 
650 7 |a Doxorubicin  |2 NLM 
650 7 |a 80168379AG  |2 NLM 
650 7 |a Polyethyleneimine  |2 NLM 
650 7 |a 9002-98-6  |2 NLM 
650 7 |a betadex  |2 NLM 
650 7 |a JV039JZZ3A  |2 NLM 
700 1 |a Cai, Kaiyong  |e verfasserin  |4 aut 
700 1 |a Hu, Yan  |e verfasserin  |4 aut 
700 1 |a Li, Jinghua  |e verfasserin  |4 aut 
700 1 |a Ding, Xingwei  |e verfasserin  |4 aut 
700 1 |a Zhang, Beilu  |e verfasserin  |4 aut 
700 1 |a Xu, Dawei  |e verfasserin  |4 aut 
700 1 |a Yang, Weihu  |e verfasserin  |4 aut 
700 1 |a Liu, Peng  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Advanced materials (Deerfield Beach, Fla.)  |d 1998  |g 24(2012), 3 vom: 17. Jan., Seite 431-5  |w (DE-627)NLM098206397  |x 1521-4095  |7 nnns 
773 1 8 |g volume:24  |g year:2012  |g number:3  |g day:17  |g month:01  |g pages:431-5 
856 4 0 |u http://dx.doi.org/10.1002/adma.201103458  |3 Volltext 
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