A qPCR-based assay to quantify oxidized guanine and other FPG-sensitive base lesions within telomeric DNA
Telomere shortening is an important risk factor for cancer and accelerated aging. However, it is becoming evident that oxidatively damaged DNA within the telomere sequence may also cause telomere dysfunction. Here we describe a reliable, cost-effective quantitative PCR (qPCR)-based method to measure...
| Veröffentlicht in: | BioTechniques. - 1993. - 51(2011), 6 vom: 15. Dez., Seite 403-11 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2011
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| Zugriff auf das übergeordnete Werk: | BioTechniques |
| Schlagworte: | Evaluation Study Journal Article Guanine 5Z93L87A1R DNA 9007-49-2 Hydrogen Peroxide BBX060AN9V DNA-Formamidopyrimidine Glycosylase EC 3.2.2.23 mehr... |
| Online verfügbar |
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