Tunable size and spectral properties of fluorescent nanoGUMBOS in modified sodium deoxycholate hydrogels

Microstructures of sodium deoxycholate hydrogels were altered considerably in the presence of variable tris(hydroxymethyl)aminomethane (TRIS) concentrations. These observations were confirmed by use of X-ray diffraction, polarized optical microscopy, rheology, and differential scanning calorimetry m...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 28(2012), 1 vom: 10. Jan., Seite 757-65
1. Verfasser: Das, Susmita (VerfasserIn)
Weitere Verfasser: de Rooy, Sergio L, Jordan, Atiya N, Chandler, Lin, Negulescu, Ioan I, El-Zahab, Bilal, Warner, Isiah M
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Hydrogels Deoxycholic Acid 005990WHZZ
LEADER 01000caa a22002652 4500
001 NLM213318121
003 DE-627
005 20240610232343.0
007 cr uuu---uuuuu
008 231224s2012 xx |||||o 00| ||eng c
024 7 |a 10.1021/la2027016  |2 doi 
028 5 2 |a pubmed24n1435.xml 
035 |a (DE-627)NLM213318121 
035 |a (NLM)22112262 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Das, Susmita  |e verfasserin  |4 aut 
245 1 0 |a Tunable size and spectral properties of fluorescent nanoGUMBOS in modified sodium deoxycholate hydrogels 
264 1 |c 2012 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 25.04.2012 
500 |a Date Revised 10.06.2024 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a Microstructures of sodium deoxycholate hydrogels were altered considerably in the presence of variable tris(hydroxymethyl)aminomethane (TRIS) concentrations. These observations were confirmed by use of X-ray diffraction, polarized optical microscopy, rheology, and differential scanning calorimetry measurements. Our studies reveal enhanced gel crystallinity and rigidity with increasing TRIS concentrations. The tunable hydrogel microstructures obtained under various conditions have been successfully utilized as templates to synthesize cyanine-based fluorescent nanoGUMBOS (nanoparticles from a group of uniform materials based on organic salts). A systematic variation in size (70-200 nm), with relatively low polydispersity and tunable spectral properties of [HMT][AOT] nanoGUMBOS, was achieved by use of these modified hydrogels. The gel microstructures are observed to direct the size as well as molecular self-assembly of the nanomaterials, thereby tuning their spectral properties. These modified hydrogels were also found to possess other interesting properties such as variable morphologies ranging from fibrous to spherulitic, variable degrees of crystallinity, rigidity, optical activity, and release profiles which can be exploited for a multitude of applications. Hence, this study demonstrates a novel method for modification of sodium deoxycholate hydrogels, their applications as templates for nanomaterials synthesis, as well as their potential applications in biotechnology and drug delivery 
650 4 |a Journal Article 
650 4 |a Research Support, N.I.H., Extramural 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Research Support, U.S. Gov't, Non-P.H.S. 
650 7 |a Hydrogels  |2 NLM 
650 7 |a Deoxycholic Acid  |2 NLM 
650 7 |a 005990WHZZ  |2 NLM 
700 1 |a de Rooy, Sergio L  |e verfasserin  |4 aut 
700 1 |a Jordan, Atiya N  |e verfasserin  |4 aut 
700 1 |a Chandler, Lin  |e verfasserin  |4 aut 
700 1 |a Negulescu, Ioan I  |e verfasserin  |4 aut 
700 1 |a El-Zahab, Bilal  |e verfasserin  |4 aut 
700 1 |a Warner, Isiah M  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Langmuir : the ACS journal of surfaces and colloids  |d 1992  |g 28(2012), 1 vom: 10. Jan., Seite 757-65  |w (DE-627)NLM098181009  |x 1520-5827  |7 nnns 
773 1 8 |g volume:28  |g year:2012  |g number:1  |g day:10  |g month:01  |g pages:757-65 
856 4 0 |u http://dx.doi.org/10.1021/la2027016  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_22 
912 |a GBV_ILN_350 
912 |a GBV_ILN_721 
951 |a AR 
952 |d 28  |j 2012  |e 1  |b 10  |c 01  |h 757-65