Magnetic nanocarriers with tunable pH dependence for controlled loading and release of cationic and anionic payloads

Magnetic nanocarriers with tunable pH dependence for controlled loading and release of cationic and anionic payloads

Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 23(2011), 47 vom: 15. Dez., Seite 5645-50
1. Verfasser: Bigall, Nadja C (VerfasserIn)
Weitere Verfasser: Curcio, Alberto, Leal, Manuel Pernia, Falqui, Andrea, Palumberi, Domenico, Di Corato, Riccardo, Albanesi, Ennio, Cingolani, Roberto, Pellegrino, Teresa
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2011
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Anions Cations Drug Carriers RNA, Small Interfering Gold 7440-57-5
Beschreibung
Zusammenfassung:Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Superparamagnetic nanocarriers with tunable pH dependence of the surface charge are designed by a simple co-precipitation method. By exploiting electrostatic interactions, cationic or anionic payloads can be adsorbed and desorbed depending on the pH. On three different resulting nanocarrier systems, experiments of loading and release of gold nanoparticles as well as effective siRNA loading and in vitro delivery on human cells are performed
Beschreibung:Date Completed 29.03.2012
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201103505