Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescents

Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescents

Copyright © 2011 Elsevier Inc. All rights reserved.

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 142(2012), 2 vom: 15. Feb., Seite 201-8
1. Verfasser: Siberry, George K (VerfasserIn)
Weitere Verfasser: Leister, Erin, Jacobson, Denise L, Foster, Samuel B, Seage, George R 3rd, Lipshultz, Steven E, Paul, Mary E, Purswani, Murli, Colin, Andrew A, Scott, Gwendolyn, Shearer, William T
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't
Beschreibung
Zusammenfassung:Copyright © 2011 Elsevier Inc. All rights reserved.
The incidence of asthma and atopic dermatitis (AD) was evaluated in HIV-infected (n = 451) compared to HIV-exposed (n = 227) but uninfected (HEU) children and adolescents by abstraction from clinical charts. Asthma was more common in HIV-infected compared to HEU children by clinical diagnosis (25% vs. 20%, p = 0.101), by asthma medication use, (31% vs. 22%, p = 0.012), and by clinical diagnosis and/or medication use, (34% vs. 25%, p = 0.012). HIV-infected children had a greater risk of asthma compared to HEU children (HR = 1.37, 95% CI: 1.01 to 1.86). AD was more common in HIV-infected than HEU children (20% vs. 12%, p = 0.009)) and children with AD were more likely to have asthma in both cohorts (41% vs. 29%, p = 0.010). HIV-infected children and adolescents in this study had an increased incidence of asthma and AD, a finding critical for millions of HIV-infected children worldwide
Beschreibung:Date Completed 11.04.2012
Date Revised 18.03.2022
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-7035
DOI:10.1016/j.clim.2011.10.005