Synthesis of length-controlled polyvalent silver nanowire-DNA conjugates for sensitive and selective detection of DNA targets

We have developed a facile method to rapidly synthesize the monodisperse silver nanowire-DNA conjugates with a constant diameter and systematically controllable lengths in the range of 0.5-2.5 μm. The synthesis of silver nanowires takes advantage of poly(sodium 4-styrenesulfonate) as a structure-dir...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1999. - 28(2012), 1 vom: 10. Jan., Seite 828-32
1. Verfasser: Han, Sang Hun (VerfasserIn)
Weitere Verfasser: Lee, Jae-Seung
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Silver 3M4G523W1G DNA 9007-49-2
Beschreibung
Zusammenfassung:We have developed a facile method to rapidly synthesize the monodisperse silver nanowire-DNA conjugates with a constant diameter and systematically controllable lengths in the range of 0.5-2.5 μm. The synthesis of silver nanowires takes advantage of poly(sodium 4-styrenesulfonate) as a structure-directing reagent and is performed under very mild conditions such as room temperature and aqueous media. The nanowires are densely conjugated with DNA sequences enough to exhibit the cooperative properties for the sensitive and selective detection of DNA targets. The limit of detection is 50 pM
Beschreibung:Date Completed 25.04.2012
Date Revised 21.11.2013
published: Print-Electronic
Citation Status MEDLINE
ISSN:1520-5827
DOI:10.1021/la203423n