The fate of 14C-radiolabelled diclofenac and 4'-hydroxydiclofenac in membrane bioreactor treatment of wastewater
This study aimed at enhancing knowledge on the fate of diclofenac (DF), together with its main human metabolite 4'-hydroxydiclofenac (4'OHDF), during wastewater treatment by using a laboratory-scale membrane bioreactor (MBR). The reactor was fed continuously with non-radiolabelled diclofen...
| Veröffentlicht in: | Water science and technology : a journal of the International Association on Water Pollution Research. - 1986. - 63(2011), 12 vom: 06., Seite 2878-85 |
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| Weitere Verfasser: | , , , |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2011
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| Zugriff auf das übergeordnete Werk: | Water science and technology : a journal of the International Association on Water Pollution Research |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Carbon Radioisotopes Membranes, Artificial Sewage Water Pollutants, Chemical Diclofenac 144O8QL0L1 4'-hydroxydiclofenac NJF5O599EF |
| Zusammenfassung: | This study aimed at enhancing knowledge on the fate of diclofenac (DF), together with its main human metabolite 4'-hydroxydiclofenac (4'OHDF), during wastewater treatment by using a laboratory-scale membrane bioreactor (MBR). The reactor was fed continuously with non-radiolabelled diclofenac for a one month period prior to a single pulse of a 14C-radiolabelled solution of DF and 4'OHDF. The solution spike contained approximately 25% 4'OHDF and 65% DF, which corresponds to the ratio observed in municipal sewage, as well as traces of two other metabolites. The radioactivity was monitored for a total of twelve days in the various output streams. The calculation of the complete mass balance in the system demonstrated that the major part of the radioactivity left the reactor with the permeate (88.7%), while 2.1% was recovered in the excess sludge. Negligible amounts were recovered in the off-gas traps and on the membranes. Chromatographic analyses of effluent samples, by means of HPLC-MS coupled in parallel to a radiodetector, displayed a different pattern than the one of the spiked solution. It showed the occurrence of three additional metabolites |
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| Beschreibung: | Date Completed 21.11.2011 Date Revised 18.09.2019 published: Print Citation Status MEDLINE |
| ISSN: | 0273-1223 |