GSNOR-mediated de-nitrosylation in the plant defence response

Crown Copyright © 2011. Published by Elsevier Ireland Ltd. All rights reserved.

Détails bibliographiques
Publié dans:Plant science : an international journal of experimental plant biology. - 1985. - 181(2011), 5 vom: 15. Nov., Seite 540-4
Auteur principal: Malik, Saad I (Auteur)
Autres auteurs: Hussain, Adil, Yun, Byung-Wook, Spoel, Steven H, Loake, Gary J
Format: Article en ligne
Langue:English
Publié: 2011
Accès à la collection:Plant science : an international journal of experimental plant biology
Sujets:Journal Article Research Support, Non-U.S. Gov't Review S-Nitrosothiols Nitric Oxide 31C4KY9ESH Aldehyde Oxidoreductases EC 1.2.- formaldehyde dehydrogenase, glutathione-independent EC 1.2.1.46 plus... Salicylic Acid O414PZ4LPZ
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520 |a Crown Copyright © 2011. Published by Elsevier Ireland Ltd. All rights reserved. 
520 |a A key feature of the plant defence response is the transient engagement of a nitrosative burst, resulting in the synthesis of reactive nitrogen intermediates (RNIs). Specific, highly reactive cysteine (Cys) residues of low pK(a) are a major site of action for these intermediates. The addition of an NO moiety to a Cys thiol to form an S-nitrosothiol (SNO), is termed S-nitrosylation. This redox-based post-translational modification is emerging as a key regulator of protein function in plant immunity. Here we highlight recent advances in our understanding of de-nitrosylation, the mechanism that depletes protein SNOs, with a focus on S-nitrosoglutathione reductase (GSNOR). This enzyme controls total cellular S-nitrosylation indirectly during the defence response by turning over S-nitrosoglutathione (GSNO), a major cache of NO bioactivity 
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650 4 |a Research Support, Non-U.S. Gov't 
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650 7 |a EC 1.2.-  |2 NLM 
650 7 |a formaldehyde dehydrogenase, glutathione-independent  |2 NLM 
650 7 |a EC 1.2.1.46  |2 NLM 
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650 7 |a O414PZ4LPZ  |2 NLM 
700 1 |a Hussain, Adil  |e verfasserin  |4 aut 
700 1 |a Yun, Byung-Wook  |e verfasserin  |4 aut 
700 1 |a Spoel, Steven H  |e verfasserin  |4 aut 
700 1 |a Loake, Gary J  |e verfasserin  |4 aut 
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