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01000caa a22002652 4500 |
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DE-627 |
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20250213014958.0 |
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231224s2011 xx ||||| 00| ||chi c |
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|a pubmed25n0701.xml
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|a (DE-627)NLM210225688
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|a (NLM)21787471
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a chi
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| 100 |
1 |
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|a Zeng, Zhao-qiu
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Clinical study of the new intelligent determination and analysis system for glomerular filtration rate
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| 264 |
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1 |
|c 2011
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 30.01.2012
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|a Date Revised 26.07.2011
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a OBJECTIVE: To discuss the clinical application value of determining glomerular filtration rate(GFR) with the new intelligent determination and analysis system for GFR (B&G System)
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| 520 |
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|a METHODS: GFR of 216 hospitalized patients suffering from the different diseases was determined accurately by clearance rate of (99m)Tc-diethylene triamine pentaacetic acid ((99m)Tc-DTPA) (Tc-GFR), and the serum creatinine (SCr) and blood urea nitrogen (BUN) were also determined. At the same time GFR was determined by B&G system and Robert formula (B&G-GFR, Robert-GFR), and creatinine clearance rate (CCr) and GFR were calculated by Cockcroft/Gault formula(CG-CCr-GFR). All the results were compared, and correlation analysis was done for the three groups of data
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| 520 |
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|a RESULTS: Among 216 patients, B&G-GFR and Tc-GFR in 106 patients with renal insufficiency and 110 patients with normal renal function showed no significant difference (ml · min(-1)· 1.73 m(-2): 29.13 ± 18.96 vs. 32.28 ± 25.03, 121.13 ± 49.79 vs. 118.48 ± 43.25, both P >0.05), while Robert-GFR (ml · min(-1) · 1.73 m(-2): 21.45 ± 15.67, 93.54 ± 30.01) and CG-CCr-GFR (ml · min(-1) · 1.73 m(-2): 11.87 ± 8.69, 86.27 ± 21.44)were significantly lower than Tc-GFR (P<0.05 or P <0.01 ). The values of B&G-GFR, Robert-GFR, CG-CCr-GFR and Tc-GFR in renal insufficiency group (ml · min(-1) · 1.73 m(-2) :6.15 ± 14.07, 13.83 ± 11.36, 23.41 ± 24.34) were respectively significantly lower than that of normal renal function group (ml · min(-1) · 1.73 m(-2):7.65 ± 6.54, 24.94 ± 13.24, 32.21 ± 21.81, all P <0.05). B&G-GFR, Robert-GFR, and CG-CCr-GFR of both groups were positively correlated with Tc-GFR (P<0.05 or P <0.01), but negatively correlated with SCr (P<0.05 or P <0.01)
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|a CONCLUSION: B&G-GFR, Robert-GFR and CG-CCr-GFR , to a certain extent, do accurately reflect GFR. However, B&G-GFR is more accurate than others, and it can take the place of Tc-GFR clinically. B&G system has the advantage of accuracy, simplicity, speed, safety and low-price compared with other methods for the determination of GFR, and it warrants popularization
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| 650 |
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|a Comparative Study
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| 650 |
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|a English Abstract
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| 650 |
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|a Journal Article
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| 650 |
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|a Research Support, Non-U.S. Gov't
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| 700 |
1 |
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|a Wu, Xi-xin
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
|d 1998
|g 23(2011), 7 vom: 13. Juli, Seite 418-20
|w (DE-627)NLM098227793
|x 1003-0603
|7 nnns
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| 773 |
1 |
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|g volume:23
|g year:2011
|g number:7
|g day:13
|g month:07
|g pages:418-20
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|a GBV_USEFLAG_A
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|a SYSFLAG_A
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| 912 |
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|a GBV_NLM
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| 912 |
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|a GBV_ILN_350
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| 951 |
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|a AR
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| 952 |
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|d 23
|j 2011
|e 7
|b 13
|c 07
|h 418-20
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