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231224s2011 xx |||||o 00| ||eng c |
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|a 10.1021/la2022177
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|a eng
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|a Bartczak, Dorota
|e verfasserin
|4 aut
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|a Preparation of peptide-functionalized gold nanoparticles using one pot EDC/sulfo-NHS coupling
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|c 2011
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 09.01.2012
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|a Date Revised 09.08.2011
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Although carbodiimides and succinimides are broadly employed for the formation of amide bonds (i.e., in amino acid coupling), their use in the coupling of peptides to water-soluble carboxylic-terminated colloidal gold nanoparticles remains challenging. In this article, we present an optimization study for the successful coupling of the KPQPRPLS peptide to spherical and rodlike colloidal gold nanoparticles. We show that the concentration, reaction time, and chemical environment are all critical to achieving the formation of robust, peptide-coated colloidal nanoparticles. Agarose gel electrophoresis was used for the characterization of conjugates
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Colloids
|2 NLM
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|a Peptides
|2 NLM
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|a Gold
|2 NLM
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|a 7440-57-5
|2 NLM
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|a Kanaras, Antonios G
|e verfasserin
|4 aut
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 27(2011), 16 vom: 16. Aug., Seite 10119-23
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|g volume:27
|g year:2011
|g number:16
|g day:16
|g month:08
|g pages:10119-23
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|u http://dx.doi.org/10.1021/la2022177
|3 Volltext
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