Enhancing the stiffness of electrospun nanofiber scaffolds with a controlled surface coating and mineralization

A new method was developed to coat hydroxyapatite (HAp) onto electrospun poly(lactic-co-glycolic acid) (PLGA) nanofibers for tendon-to-bone insertion site repair applications. Prior to mineralization, chitosan and heparin were covalently immobilized onto the surface of the fibers to accelerate the n...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 27(2011), 15 vom: 02. Aug., Seite 9088-93
1. Verfasser: Liu, Wenying (VerfasserIn)
Weitere Verfasser: Yeh, Yi-Chun, Lipner, Justin, Xie, Jingwei, Sung, Hsing-Wen, Thomopoulos, Stavros, Xia, Younan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2011
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Polylactic Acid-Polyglycolic Acid Copolymer 1SIA8062RS Polyglycolic Acid 26009-03-0 Lactic Acid 33X04XA5AT mehr... Heparin 9005-49-6 Chitosan 9012-76-4 Durapatite 91D9GV0Z28