The role of CYP1A inhibition in the embryotoxic interactions between hypoxia and polycyclic aromatic hydrocarbons (PAHs) and PAH mixtures in zebrafish (Danio rerio)

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants with elevated concentrations in waters that may also experience hypoxia. Previous research has shown interactions between hypoxia and some PAHs (fluoranthene, α-naphthoflavone) but no interaction with others (benzo[a]pyr...

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Publié dans:Ecotoxicology (London, England). - 1998. - 20(2011), 6 vom: 21. Aug., Seite 1300-14
Auteur principal: Fleming, Carrie R (Auteur)
Autres auteurs: Di Giulio, Richard T
Format: Article en ligne
Langue:English
Publié: 2011
Accès à la collection:Ecotoxicology (London, England)
Sujets:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Dioxins Enzyme Inhibitors Polycyclic Aromatic Hydrocarbons Receptors, Aryl Hydrocarbon Water Pollutants, Chemical Polychlorinated Biphenyls DFC2HB4I0K plus... Cytochrome P-450 CYP1A1 EC 1.14.14.1 3,4,5,3',4'-pentachlorobiphenyl TSH69IA9XF