The role of CYP1A inhibition in the embryotoxic interactions between hypoxia and polycyclic aromatic hydrocarbons (PAHs) and PAH mixtures in zebrafish (Danio rerio)

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants with elevated concentrations in waters that may also experience hypoxia. Previous research has shown interactions between hypoxia and some PAHs (fluoranthene, α-naphthoflavone) but no interaction with others (benzo[a]pyr...

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Veröffentlicht in:Ecotoxicology (London, England). - 1998. - 20(2011), 6 vom: 21. Aug., Seite 1300-14
1. Verfasser: Fleming, Carrie R (VerfasserIn)
Weitere Verfasser: Di Giulio, Richard T
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2011
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Dioxins Enzyme Inhibitors Polycyclic Aromatic Hydrocarbons Receptors, Aryl Hydrocarbon Water Pollutants, Chemical Polychlorinated Biphenyls DFC2HB4I0K mehr... Cytochrome P-450 CYP1A1 EC 1.14.14.1 3,4,5,3',4'-pentachlorobiphenyl TSH69IA9XF