Serum biochemical analysis to indicate pathogenic risk on mouse Mus musculus exposure to source of drinking water

The 18 biochemical parameters of serum were measured to analyze the pathogenic risks of the Yangtze River Source of Drinking Water in Nanjing area (YZR-SDW-NJ) on mouse Mus musculus for protection of human health in this research. The male mice Mus musculus were sampled and fed with YZR-SDW-NJ for 9...

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Veröffentlicht in:Ecotoxicology (London, England). - 1998. - 20(2011), 5 vom: 05. Juli, Seite 1078-82
1. Verfasser: Yun, Shi Feng (VerfasserIn)
Weitere Verfasser: Tian, Xiao Yun, Cheng, Shu Pei, Zhang, Yan, Li, Ai Min, Zhang, Li Bo, Zhang, Xu Xiang, Chen, Li, Wu, Bing, Guo, Lian Qin, Shi, Yun Zhong
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2011
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Polycyclic Aromatic Hydrocarbons Water Pollutants, Chemical Alanine Transaminase EC 2.6.1.2
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520 |a The 18 biochemical parameters of serum were measured to analyze the pathogenic risks of the Yangtze River Source of Drinking Water in Nanjing area (YZR-SDW-NJ) on mouse Mus musculus for protection of human health in this research. The male mice Mus musculus were sampled and fed with YZR-SDW-NJ for 90 days then the eighteen serum biochemical levels were measured with Automatic Biochemical Analysis/RerLi 600. And the parameter data were treated by One-Way ANOVA statistic approach. The results showed that five parameter levels for the sample group mice were different from those for the control group significantly (0.01 < P or 0.05 < P). Four 4 of the 5 altered parameter levels were decreased including glutamate pyruvate transaminase 38% lower, glutamine-oxaloacetic transaminase 24% lower, triglyceride 76% lower and cystatin C 73% lower, only creatinine level was 26% higher than that in the control group. The data suggest that YZR-SDW-NJ had toxicity on the mouse and the organic pollutants in YZR-SDW-NJ might lead to liver, kidney, cardiovascular and metabolic pathogenic risks on the human beings. The results might be cited as evidence to control pollutants in the source water for the protection of NJ people's health 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
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650 7 |a Water Pollutants, Chemical  |2 NLM 
650 7 |a Alanine Transaminase  |2 NLM 
650 7 |a EC 2.6.1.2  |2 NLM 
700 1 |a Tian, Xiao Yun  |e verfasserin  |4 aut 
700 1 |a Cheng, Shu Pei  |e verfasserin  |4 aut 
700 1 |a Zhang, Yan  |e verfasserin  |4 aut 
700 1 |a Li, Ai Min  |e verfasserin  |4 aut 
700 1 |a Zhang, Li Bo  |e verfasserin  |4 aut 
700 1 |a Zhang, Xu Xiang  |e verfasserin  |4 aut 
700 1 |a Chen, Li  |e verfasserin  |4 aut 
700 1 |a Wu, Bing  |e verfasserin  |4 aut 
700 1 |a Guo, Lian Qin  |e verfasserin  |4 aut 
700 1 |a Shi, Yun Zhong  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Ecotoxicology (London, England)  |d 1998  |g 20(2011), 5 vom: 05. Juli, Seite 1078-82  |w (DE-627)NLM098212214  |x 1573-3017  |7 nnns 
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