Comparative analysis of binding affinities between styrene and mammalian CYP2E1 by bioinformatics approaches

Cytochrome P450 2E1 (CYP2E1) is a cytochrome P450 enzyme involved in styrene metabolism. This study compared the binding affinities between styrene and 11 mammalian CYP2E1 systems using bioinformatics methods. Firstly, amino acid sequences of CYP2E1s were obtained from the Swiss-Prot database. Then,...

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Veröffentlicht in:Ecotoxicology (London, England). - 1992. - 20(2011), 5 vom: 28. Juli, Seite 1041-6
1. Verfasser: Wu, Bing (VerfasserIn)
Weitere Verfasser: Sun, Jie, Cheng, Shu-Pei, Gu, Ji-Dong, Li, Ai-Min, Zhang, Xu-Xiang
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2011
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Comparative Study Journal Article Research Support, Non-U.S. Gov't Environmental Pollutants Styrene 44LJ2U959V Cytochrome P-450 CYP2E1 EC 1.14.13.-