Hydroxyl radical generation and oxidative stress in earthworms (Eisenia fetida) exposed to decabromodiphenyl ether (BDE-209)

Antioxidant responses induced by decabromodiphenyl ether (BDE-209) in the earthworms (Eisenia fetida) were studied after 7 days of exposure. Electron paramagnetic resonance (EPR) spectra indicated that hydroxyl radicals (•OH) in earthworms were significantly induced by 0.01-10 mg/kg of BDE-209. Malo...

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Veröffentlicht in:Ecotoxicology (London, England). - 1992. - 20(2011), 5 vom: 28. Juli, Seite 993-9
1. Verfasser: Xie, Xianchuan (VerfasserIn)
Weitere Verfasser: Wu, Yingxin, Zhu, Mengying, Zhang, You-kuan, Wang, Xiaorong
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2011
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Halogenated Diphenyl Ethers Soil Pollutants Hydroxyl Radical 3352-57-6 Malondialdehyde 4Y8F71G49Q Catalase EC 1.11.1.6 mehr... Superoxide Dismutase EC 1.15.1.1 Glutathione Transferase EC 2.5.1.18 Glutathione GAN16C9B8O decabromobiphenyl ether N80BQ29A0H Glutathione Disulfide ULW86O013H
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520 |a Antioxidant responses induced by decabromodiphenyl ether (BDE-209) in the earthworms (Eisenia fetida) were studied after 7 days of exposure. Electron paramagnetic resonance (EPR) spectra indicated that hydroxyl radicals (•OH) in earthworms were significantly induced by 0.01-10 mg/kg of BDE-209. Malondialdehyde (MDA) and protein carbonyl (PCO) were stimulated at 0.5-10 mg/kg and 1-10 mg/kg, respectively. The reduced glutathione (GSH) was inhibited at 1-10 mg/kg while oxidized glutathione (GSSG) accumulated at 0.5-10 mg/kg. The GSH/GSSG ratio decreased at 0.5-10 mg/kg, and superoxide dismutase (SOD) and glutathione-S-transferase (GST) activities were induced at 0.1-1 and 0.5 mg/kg, respectively and both decreased at 10 mg/kg. Catalase (CAT) activities increased at 1-10 mg/kg. The results showed that severe oxidative stress occurred in E. fetida, and may play an important role in inducing the toxicity of BDE-209 on earthworms 
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700 1 |a Wu, Yingxin  |e verfasserin  |4 aut 
700 1 |a Zhu, Mengying  |e verfasserin  |4 aut 
700 1 |a Zhang, You-kuan  |e verfasserin  |4 aut 
700 1 |a Wang, Xiaorong  |e verfasserin  |4 aut 
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