|
|
|
|
| LEADER |
01000caa a22002652 4500 |
| 001 |
NLM206207638 |
| 003 |
DE-627 |
| 005 |
20231227124339.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231223s2011 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1093/jxb/err007
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1222.xml
|
| 035 |
|
|
|a (DE-627)NLM206207638
|
| 035 |
|
|
|a (NLM)21357769
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Langhans, Markus
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Differential effects of the brefeldin A analogue (6R)-hydroxy-BFA in tobacco and Arabidopsis
|
| 264 |
|
1 |
|c 2011
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 06.09.2011
|
| 500 |
|
|
|a Date Revised 13.12.2023
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a The effects of two brefeldin A (BFA) analogues (BFA lactam; 6(R)-hydroxy-BFA) on plant cells were tested. Although these two compounds elicited BFA-like effects in mammalian cells, the lactam analogue failed to elicit a response in plant cells. By contrast, while the 6(R)-hydroxy-BFA analogue gave rise to a classic BFA response in tobacco mesophyll protoplasts and true leaves of Arabidopsis (redistribution of Golgi enzymes into the ER), it failed to cause the formation of BFA-compartments in Arabidopsis root cells and cotyledonary leaves. Even when the GNL1-LM mutant of Arabidopsis, which has a cis-Golgi located BFA-sensitive ARF-GEF, was used, the 6(R)-hydroxy analogue failed to elicit a response at conventional BFA concentrations. Only at concentrations of over 200 μM did 6(R)-hydroxy-BFA elicit a BFA-like effect. These differences are interpreted in terms of the different properties of the respective TGN- (Arabidopsis roots) and cis-Golgi- (tobacco mesophyll) localized BFA-sensitive ARF-GEFs
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 650 |
|
7 |
|a Arabidopsis Proteins
|2 NLM
|
| 650 |
|
7 |
|a Biomarkers
|2 NLM
|
| 650 |
|
7 |
|a GNL1 protein, Arabidopsis
|2 NLM
|
| 650 |
|
7 |
|a Guanine Nucleotide Exchange Factors
|2 NLM
|
| 650 |
|
7 |
|a Brefeldin A
|2 NLM
|
| 650 |
|
7 |
|a 20350-15-6
|2 NLM
|
| 700 |
1 |
|
|a Förster, Sebastian
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Helmchen, Günter
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Robinson, David G
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 62(2011), 8 vom: 28. Mai, Seite 2949-57
|w (DE-627)NLM098182706
|x 1460-2431
|7 nnns
|
| 773 |
1 |
8 |
|g volume:62
|g year:2011
|g number:8
|g day:28
|g month:05
|g pages:2949-57
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1093/jxb/err007
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 62
|j 2011
|e 8
|b 28
|c 05
|h 2949-57
|