Self-assembly of short aβ(16-22) peptides : effect of terminal capping and the role of electrostatic interaction

We report the characterization of self-assembly of two short β-amyloid (Aβ) peptides (16-22), KLVFFAE and Ac-KLVFFAE-NH2, focusing on examining the effect of terminal capping. At pH 2.0, TEM and AFM imaging revealed that the uncapped peptide self-assembled into long, straight, and unbranched nanofib...

Description complète

Détails bibliographiques
Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 27(2011), 6 vom: 15. März, Seite 2723-30
Auteur principal: Tao, Kai (Auteur)
Autres auteurs: Wang, Jiqian, Zhou, Peng, Wang, Chengdong, Xu, Hai, Zhao, Xiubo, Lu, Jian R
Format: Article en ligne
Langue:English
Publié: 2011
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Amyloid beta-Peptides Peptide Fragments amyloid beta-protein (16-22)