Clinicopathological characteristics and potential etiologies of neonatal spontaneous gastric perforation

OBJECTIVE: To study the etiology and clinicopathological features of neonatal spontaneous gastric perforation

Bibliographische Detailangaben
Veröffentlicht in:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 48(2010), 10 vom: 20. Okt., Seite 779-82
1. Verfasser: Wang, Zhi-qiang (VerfasserIn)
Weitere Verfasser: Xie, Li-wei, Wu, Hong-fang, Wang, Zong-min
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Zhonghua er ke za zhi = Chinese journal of pediatrics
Schlagworte:English Abstract Journal Article
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100 1 |a Wang, Zhi-qiang  |e verfasserin  |4 aut 
245 1 0 |a Clinicopathological characteristics and potential etiologies of neonatal spontaneous gastric perforation 
264 1 |c 2010 
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500 |a Date Revised 07.06.2016 
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520 |a OBJECTIVE: To study the etiology and clinicopathological features of neonatal spontaneous gastric perforation 
520 |a METHODS: The clinical data of 15 cases with neonatal gastric perforation seen from 2001 to 2009 were retrospectively analyzed. Immunohistochemical staining was adopted for all the cases 
520 |a RESULTS: The typical clinical manifestations of this disease were vomiting, abdominal distention and respiratory distress. Abdominal orthostatic X-ray showed free gas under diaphragm and seroperitoneum. In most of the cases the stomach perforation occurred at the greater curvature. Eight of the cases died in this group, the mortality was 53.33%. Six of the deaths occurred within 1 day after birth with symptoms. There were thinning and defect of stomach wall muscle and interstitial cells of Cajal (ICC) reduction as demonstrated by microscope 
520 |a CONCLUSIONS: Spontaneous neonatal gastric perforation is associated with abnormal gastric wall structure and reduction of ICC. Prognosis is closely related to the time of onset and the timely surgical operation 
650 4 |a English Abstract 
650 4 |a Journal Article 
700 1 |a Xie, Li-wei  |e verfasserin  |4 aut 
700 1 |a Wu, Hong-fang  |e verfasserin  |4 aut 
700 1 |a Wang, Zong-min  |e verfasserin  |4 aut 
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