Relative sensitivity of fish and mammalian cells to the antibiotic, trimethoprim : cytotoxic and genotoxic responses as determined by neutral red retention, Comet and micronucleus assays

Relative cytotoxicity and genotoxicity of a widely used antibiotic, trimethoprim (TRIMP) was evaluated under in vitro conditions using rainbow trout gonad-2 (RTG-2) and Chinese hamster ovary-K1 (CHO-K1) cells. Whilst cytotoxicity was determined using neutral red retention (NRR) assay, the genotoxici...

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Bibliographische Detailangaben
Veröffentlicht in:Ecotoxicology (London, England). - 1992. - 20(2011), 1 vom: 16. Jan., Seite 208-17
1. Verfasser: Papis, Elena (VerfasserIn)
Weitere Verfasser: Davies, Simon J, Jha, Awadhesh N
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2011
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Anti-Bacterial Agents Water Pollutants, Chemical Neutral Red 261QK3SSBH Trimethoprim AN164J8Y0X