Changes in clinical manifestations of Mycoplasma pneumoniae pneumonia in children older than 3 years during 2000 - 2006 in Hangzhou

OBJECTIVE: To reveal changes in clinical manifestations of Mycoplasma pneumoniae (Mp) pneumonia in children older than 3 years of age during 2000 - 2006

Bibliographische Detailangaben
Veröffentlicht in:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 48(2010), 7 vom: 01. Juli, Seite 531-4
1. Verfasser: Zhang, Bing (VerfasserIn)
Weitere Verfasser: Chen, Zhi-min
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Zhonghua er ke za zhi = Chinese journal of pediatrics
Schlagworte:English Abstract Journal Article Research Support, Non-U.S. Gov't
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245 1 0 |a Changes in clinical manifestations of Mycoplasma pneumoniae pneumonia in children older than 3 years during 2000 - 2006 in Hangzhou 
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500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To reveal changes in clinical manifestations of Mycoplasma pneumoniae (Mp) pneumonia in children older than 3 years of age during 2000 - 2006 
520 |a METHOD: Totally 288 older children with Mp pneumonia hospitalized in the hospital between 2000 and 2006 were enrolled. Clinical manifestation, chest X-ray and clinical outcomes among three time periods (2000 - 2002, 2003 - 2004, 2005 - 2006) were compared 
520 |a RESULT: (1) Fever and its duration; 281 cases (97.6%) had fever of different duration (median = 7.2 d, 8.5 d, and 11.2 d, respectively) among the time periods, showing statistically significant difference (P < 0.01). (2) Respiratory symptoms: different incidence of wheezing/dyspnea (6.1%, 9.9%, 16.3%), thrilling (6.9%, 11.3%, 19.8%) and chest pain (12.2%, 15.5%, 22.1%) among different time periods had significant difference (χ(2) = 5.87, 11.46, 5.21, P < 0.05). (3) The incidence of extrapulmonary damages (13.0%, 38.0%, 48.8%) among different time periods also had significant difference (χ(2) = 21.27, P < 0.01). (4) Chest X-ray examination showed large area of lesions in most cases; 30.2% of cases seen during 2005 - 2006 were found having pulmonary complications such as pleural effusion or atelectasis. The incidences of pulmonary complications among different time periods had significant difference (P < 0.01). (5) TREATMENT AND OUTCOME: after comparing the efficacy of erythromycin or azithromycin, decline of clinical effectiveness was revealed among different time periods (P < 0.05). The duration of fever after macrolide administration (median = 3.2 d, 4.5 d, 6.2 d, respectively) and hospital stay (median = 7.0 d, 8.7 d, and 11.4 d, respectively) among different time periods showed significant differences (P < 0.05) 
520 |a CONCLUSION: More refractory and severe Mp pneumonia cases appeared during 2000 - 2006 in children older than 3 years of age in Hangzhou, with prolonged fever duration, aggravated respiratory symptoms and more complications and extrapulmonary damages 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
700 1 |a Chen, Zhi-min  |e verfasserin  |4 aut 
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