In vitro model on glass surfaces for complex interactions between different types of cells

In vitro model on glass surfaces for complex interactions between different types of cells

This report establishes an in vitro model on glass surfaces for patterning multiple types of cells to simulate cell-cell interactions in vivo. The model employs a microfluidic system and poly(ethylene glycol)-terminated oxysilane (PEG-oxysilane) to modify glass surfaces in order to resist cell adhes...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 23 vom: 07. Dez., Seite 17790-4
1. Verfasser: Chen, Zhenling (VerfasserIn)
Weitere Verfasser: Chen, Wei, Yuan, Bo, Xiao, Le, Liu, Dingbin, Jin, Yu, Quan, Baogang, Wang, Jia-ou, Ibrahim, Kurash, Wang, Zhuo, Zhang, Wei, Jiang, Xingyu
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Silanes Polyethylene Glycols 3WJQ0SDW1A Oxygen S88TT14065
Beschreibung
Zusammenfassung:This report establishes an in vitro model on glass surfaces for patterning multiple types of cells to simulate cell-cell interactions in vivo. The model employs a microfluidic system and poly(ethylene glycol)-terminated oxysilane (PEG-oxysilane) to modify glass surfaces in order to resist cell adhesion. The system allows the selective confinement of different types of cells to realize complete confinement, partial confinement, and no confinement of three types of cells on glass surfaces. The model was applied to study intercellular interactions among human umbilical vein endothelial cells (HUVEC), PLA 801 C and PLA801 D cells
Beschreibung:Date Completed 06.04.2011
Date Revised 01.12.2018
published: Print-Electronic
Citation Status MEDLINE
ISSN:1520-5827
DOI:10.1021/la103132m