Complex surface concentration gradients by stenciled "electro click chemistry"
Complex one- or two-dimensional concentration gradients of alkynated molecules are produced on azidized conducting polymer substrates by stenciled "electro click chemistry". The latter describes the local electrochemical generation of catalytically active Cu(I) required to complete a "...
| Publié dans: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 26(2010), 20 vom: 19. Okt., Seite 16171-7 |
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| Auteur principal: | |
| Autres auteurs: | , , , , |
| Format: | Article en ligne |
| Langue: | English |
| Publié: |
2010
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| Accès à la collection: | Langmuir : the ACS journal of surfaces and colloids |
| Sujets: | Journal Article Research Support, Non-U.S. Gov't Alkynes Bridged Bicyclo Compounds, Heterocyclic Immobilized Proteins Oligopeptides Polymers poly(3,4-ethylene dioxythiophene) Copper 789U1901C5 plus... |
| Résumé: | Complex one- or two-dimensional concentration gradients of alkynated molecules are produced on azidized conducting polymer substrates by stenciled "electro click chemistry". The latter describes the local electrochemical generation of catalytically active Cu(I) required to complete a "click reaction" between alkynes and azides at room temperature. A stencil on the counter electrode defines the shape and multiplicity of the gradient(s) on the conducting polymer substrate, while the specific reaction conditions control gradient steepness and the maximum concentration deposited. Biologically active ligands including cell binding peptides are patterned in gradients by this method without losing their biological function or the conductivity of the polymer |
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| Description: | Date Completed 21.01.2011 Date Revised 25.11.2016 published: Print Citation Status MEDLINE |
| ISSN: | 1520-5827 |
| DOI: | 10.1021/la102652p |