Peptide-Functionalized Click Hydrogels with Independently Tunable Mechanics and Chemical Functionality for 3D Cell Culture
Multifunctionalized macromers react via a copper-free click chemistry to form an idealized 3D hydrogel. Subsequently, thiol-containing biomolecules are spatially patterned within the material with precise control over the amount and location of functionalization. Both the network formation and subse...
Veröffentlicht in: | Chemistry of materials : a publication of the American Chemical Society. - 1998. - 22(2010), 16 vom: 24. Aug., Seite 4783-4790 |
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1. Verfasser: | |
Weitere Verfasser: | , |
Format: | Aufsatz |
Sprache: | English |
Veröffentlicht: |
2010
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Zugriff auf das übergeordnete Werk: | Chemistry of materials : a publication of the American Chemical Society |
Schlagworte: | Journal Article |
Zusammenfassung: | Multifunctionalized macromers react via a copper-free click chemistry to form an idealized 3D hydrogel. Subsequently, thiol-containing biomolecules are spatially patterned within the material with precise control over the amount and location of functionalization. Both the network formation and subsequent patterning reactions are fully cytocompatible, allowing these systems to be used to study individual cell behavior at user-defined locations throughout the material |
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Beschreibung: | Date Revised 20.10.2021 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
ISSN: | 0897-4756 |