Interaction of n-octyl β,D-glucopyranoside with giant magnetic-fluid-loaded phosphatidylcholine vesicles : direct visualization of membrane curvature fluctuations as a function of surfactant partitioning between water and lipid bilayer

The present study deals with the morphological modifications of giant dioleoyl phosphatidylcholine vesicles (DOPC GUVs) induced by the nonionic surfactant n-octyl β,D-glucopyranoside at sublytic levels, i.e., in the first steps of the vesicle-to-micelle transition process, when surfactant inserts in...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 19 vom: 05. Okt., Seite 15453-63
1. Verfasser: Ménager, Christine (VerfasserIn)
Weitere Verfasser: Guemghar, Dihya, Cabuil, Valérie, Lesieur, Sylviane
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Glucosides Lipid Bilayers Phosphatidylcholines Surface-Active Agents octyl-beta-D-glucoside 29836-26-8
Beschreibung
Zusammenfassung:The present study deals with the morphological modifications of giant dioleoyl phosphatidylcholine vesicles (DOPC GUVs) induced by the nonionic surfactant n-octyl β,D-glucopyranoside at sublytic levels, i.e., in the first steps of the vesicle-to-micelle transition process, when surfactant inserts into the vesicle bilayer without disruption. Experimental conditions were perfected to exactly control the surfactant bilayer composition of the vesicles, in line with former work focused on the mechanical properties of the membrane of magnetic-fluid-loaded DOPC GUVs submitted to a magnetic field. The purpose here was to systematically examine, in the absence of any external mechanical constraint, the dynamics of giant vesicle shape and membrane deformations as a function of surfactant partitioning between the aqueous phase and the lipid membrane, beforehand established by turbidity measurements from small unilamellar vesicles
Beschreibung:Date Completed 03.01.2011
Date Revised 29.09.2010
published: Print
Citation Status MEDLINE
ISSN:1520-5827
DOI:10.1021/la102532h