Phase behavior of ketoprofen-poly(lactic acid) drug particles formed by rapid expansion of supercritical solutions

The present contribution investigates whether it is possible to form stable amorphous particles of ketoprofen-poly(lactic acid), naproxen-poly(lactic acid), and indomethacin-poly(lactic acid). Amorphization and micronization of these poorly water-soluble drugs offer a combined way to improve the sol...

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Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 18 vom: 21. Sept., Seite 14951-7
1. Verfasser:	Imran ul-haq, Muhammad (VerfasserIn)
Weitere Verfasser:	Chasovskikh, Egor, Signorell, Ruth
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2010
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Polyesters Polymers Solutions Lactic Acid 33X04XA5AT poly(lactide) 459TN2L5F5 Naproxen mehr... 57Y76R9ATQ Ketoprofen 90Y4QC304K Indomethacin XXE1CET956