Tunable leuko-polymersomes that adhere specifically to inflammatory markers

The polymersome, a fully synthetic cell mimetic, is a tunable platform for drug delivery vehicles to detect and treat disease (theranostics). Here, we design a leuko-polymersome, a polymersome with the adhesive properties of leukocytes, which can effectively bind to inflammatory sites under flow. We...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 17 vom: 07. Sept., Seite 14089-96
1. Verfasser: Robbins, Gregory P (VerfasserIn)
Weitere Verfasser: Saunders, Randi L, Haun, Jered B, Rawson, Jeff, Therien, Michael J, Hammer, Daniel A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Antibodies Biomarkers Butadienes Drug Carriers Elastomers Ligands Oligosaccharides mehr... P-Selectin Sialyl Lewis X Antigen Intercellular Adhesion Molecule-1 126547-89-5 Polyethylene Glycols 3WJQ0SDW1A polybutadiene 9003-17-2 biocytin G6D6147J22 Lysine K3Z4F929H6