Polymeric crowding agents improve passive biomacromolecule encapsulation in lipid vesicles

Large solutes such as high molecular weight proteins can be difficult to encapsulate in lipid vesicles. Passive trapping of these macromolecular solutes during vesicle formation typically results in concentrations inside the vesicles that are much lower than in the external solution. Here, we invest...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 16 vom: 17. Aug., Seite 13195-200
1. Verfasser: Dominak, Lisa M (VerfasserIn)
Weitere Verfasser: Omiatek, Donna M, Gundermann, Erica L, Heien, Michael L, Keating, Christine D
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Dextrans Unilamellar Liposomes Polyethylene Glycols 3WJQ0SDW1A