Programmed assembly of peptide-functionalized gold nanoparticles on DNA templates

We present a novel nanoparticle building block system based on the interactions between short synthetic oligonucleotides and peptides. Gold nanoparticles coated with DNA-binding peptides can be attached to self-organized oligonucleotide templates to formulate well-ordered structures of nanoparticles...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 17 vom: 07. Sept., Seite 13760-2
1. Verfasser: Coomber, Danielle (VerfasserIn)
Weitere Verfasser: Bartczak, Dorota, Gerrard, Simon R, Tyas, Sarah, Kanaras, Antonios G, Stulz, Eugen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Oligonucleotides Peptides Gold 7440-57-5 DNA 9007-49-2
Beschreibung
Zusammenfassung:We present a novel nanoparticle building block system based on the interactions between short synthetic oligonucleotides and peptides. Gold nanoparticles coated with DNA-binding peptides can be attached to self-organized oligonucleotide templates to formulate well-ordered structures of nanoparticles. By regulating the amount of DNA-binding peptide attached to the nanoparticle surface and using specifically designed oligonucleotides, the nanoparticle assembly can be controlled to form dimers, trimers, and adjustable-length nanoparticle chains as well as more complex structures
Beschreibung:Date Completed 27.12.2010
Date Revised 02.09.2010
published: Print
Citation Status MEDLINE
ISSN:1520-5827
DOI:10.1021/la1023554